Survival analysis of pulpectomy in primary molars performed under dental general anaesthesia: a two-year retrospective study

• Published in: BMC oral health Vol. 22; no. 1; p. 597
• Main Authors: Xie, Yongting, Wang, Yan, Ma, Qizhao, Li, Jing, Chen, Yandi, Yang, Ran, Huang, Ruijie, Zhang, Qiong, Zou, Jing
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 10.12.2022; BioMed Central; BMC
• Subjects: Aluminum Compounds; Anesthesia; Anesthesia, General; Biocompatibility; Calcium Compounds - therapeutic use; Child; Dental pulp; Dentists; Diagnosis; Drug Combinations; Endodontics; Failure analysis; Female; Gender; General anesthesia; Humans; Male; Medical records; Mineral trioxide aggregate; Molars; Oxides; Pediatrics; Periapical Periodontitis; Periodontitis; Primary molars; Pulpectomy; Pulpitis; Regression analysis; Retrospective Studies; Risk factors; Silicates; Statistical analysis; Success; Success rate; Survival; Survival Analysis; Systematic review; Teeth; Tooth, Deciduous; Treatment Outcome; China; Japan; Primary molars; Survival analysis; Success rate; Mineral trioxide aggregate; Pulpectomy
• ISSN: 1472-6831; 1472-6831
• DOI: 10.1186/s12903-022-02553-z

To retrospectively investigate the success rate of primary-molar pulpectomy performed under general anaesthesia and the potential risk factors that affect the 24-month success rate. The case data and two-year follow-up records of children (aged 3-6 years) who received pulpectomy in primary molars performed under general anaesthesia were reviewed and assessed. Potential risk factors included age, gender, decayed-missing-filled teeth, endodontic diagnosis, tooth location, and postobturation sealing of the pulp chamber floor with MTA. With a two-year follow-up period, the outcomes of all the primary molars were classified into success and failure. Survival analysis was used to assess the outcomes. The Kaplan-Meier method was used to analyse the success rate. Univariate and multivariate Cox proportional hazards regression models were used to evaluate the potential risk factors associated with the overall survival of primary molars. A total of 410 teeth from 163 children (88 boys and 75 girls) were included in this study. The overall two-year success rate was 66.1% for all primary molars. The mean overall survival time for this study was 22.1 (95% CI, 21.73‒22.48) months. Multivariate Cox regression analysis demonstrated that endodontic diagnosis (irreversible pulpitis or periapical periodontitis), tooth location (maxillary or mandibular primary molar), and postobturation sealing of the pulp chamber floor (MTA or no-MTA) were significant risk factors for overall survival in this study (P < .05). The differences in success rates were not statistically significant in terms of age, gender, and decayed-missing-filled teeth (P > .05). When compared to teeth diagnosed with irreversible pulpitis, those with periapical periodontitis failed more frequently. Postobturation sealing of the pulp chamber floor with MTA improved the success rate of pulpectomy in primary molars, especially when the inflammation did not spread to the periradicular area.