Magnetically controlled growing rods in the management of early onset scoliosis: a systematic review

• Published in: Journal of orthopaedic surgery and research Vol. 17; no. 1; p. 309
• Main Authors: Migliorini, Filippo, Chiu, Wai On, Scrofani, Raffaele, Chiu, Wai Kwong, Baroncini, Alice, Iaconetta, Giorgio, Maffulli, Nicola
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 11.06.2022; BioMed Central; BMC
• Subjects: Analysis; Backache; Bone healing; Child; Clinical trials; Deformity; Early onset scoliosis; Evidence-based medicine; Female; Follow-Up Studies; Humans; Kyphosis; Kyphosis - surgery; Magnetically controlled growing rods; Male; MCGR; Medical research; Medicine, Experimental; Orthopedics; Patients; Postoperative Complications; Retrospective Studies; Rods; Scoliosis; Scoliosis - surgery; Spine; Spine - surgery; Systematic Review; Treatment Outcome; Vertebrae; Wound healing; Deformity; Early onset scoliosis; MCGR; Spine; Magnetically controlled growing rods
• ISSN: 1749-799X; 1749-799X
• DOI: 10.1186/s13018-022-03200-7

Early onset scoliosis (EOS) presents in patients younger than 10 years. Magnetically controlled growing rods (MCGR) were developed as an outpatient distraction system for EOS, allowing to avoid multiple surgeries. This systematic review investigated the efficacy and feasibility of MCGR in EOS. This systematic review was conducted according to the PRISMA guidelines. PubMed, Google scholar, Embase, and Scopus were accessed in May 2022. All the clinical trials which investigate the role of MCGR for early onset scoliosis were accessed. Only studies reporting data in patients younger than 10 years with a preoperative Cobb Angle greater than 40° were eligible. The following data was extracted at baseline and at last follow-up: mean kyphosis angle, overall mean Cobb angle, mean T1-S1 length. Data from complication were also collected. Data from 23 clinical studies (504 patients) were included in the present study. 56% (282 of 504) were females. The average length of the follow-up was 28.9 ± 16.0 months. The mean age of the patients was 8.7 ± 1.9 years old. The mean BMI was 17.7 ± 7.6 kg/m . The mean kyphosis angle had reduced by the last follow-up (P = 0.04), as did the overall mean Cobb angle (P < 0.0001), while the overall T1-S1 length increased (P = 0.0002). Implant-associated complications, followed by spinal alignment failure, wound healing ailments, pulmonary complications, progressive trunk stiffness, persistent back pain, and fracture. The management of EOS remains challenging. The current evidence indicates that MCGR may be effective to distract the spine and model the curve in EOS.