HBV-Specific Adaptive Immunity

The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of...

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Published inViruses Vol. 1; no. 2; pp. 91 - 103
Main Authors Bertoletti, Antonio, Tan, Anthony T, Gehring, Adam J
Format Journal Article Book Review
LanguageEnglish
Published Switzerland MDPI AG 01.09.2009
Molecular Diversity Preservation International (MDPI)
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Summary:The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of HBV immunity in patients with resolved or chronic HBV infection and analyze how the liver environment can directly modulate HBV-immunity.
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ISSN:1999-4915
1999-4915
DOI:10.3390/v1020091