Epidemiological statistics of congenital thumb duplication in the Chinese population

• Published in: Journal of orthopaedic surgery and research Vol. 16; no. 1; pp. 481 - 5
• Main Authors: Yao, Yingling, Zhou, Haolin, Li, Lianyong, Nan, Guoxin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.08.2021; BioMed Central; BMC
• Subjects: Birth defects; China - epidemiology; Classification; Congenital defects; Epidemiology; Ethnicity; Female; Females; Fingers & toes; Gender; Genetic disorders; Hospitals; Humans; Male; Males; Northeast China; Orthopedics; Polydactyly; Polydactyly - diagnostic imaging; Polydactyly - epidemiology; Population; Southwest China; Statistical analysis; Statistics; Thumb - abnormalities; Thumb - diagnostic imaging; Thumb duplication; Thumb polydactyly; Wassel classification; China; Japan; Turkey; Wassel classification; Northeast China; Southwest China; Thumb polydactyly; Thumb duplication
• ISSN: 1749-799X; 1749-799X
• DOI: 10.1186/s13018-021-02567-3

Thumb duplication is a very common congenital malformation. This study describes and compares the phenotypic manifestations of polydactyly between southwest and northeast China. However, previous studies had a limited sample size. Therefore, this study used a large sample. A total of 3549 well-characterized thumb duplication cases were divided into group A (southwest China) and group B (northeast China). In group A and group B, the left-to-right ratio was 1:1.5 and 1:1.75, respectively, and the female-to-male ratio was 1:1.5 and 1:1.58, respectively. There were no significant differences in gender distribution or the distribution of left and right polydactyly between the two groups, but the distribution of bilateral polydactyly was significantly different.