Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules

• Published in: BMC endocrine disorders Vol. 22; no. 1; pp. 145 - 15
• Main Authors: Zhang, Ziwei, Lin, Ning
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 31.05.2022; BioMed Central; BMC
• Subjects: ACR score; ACR TI-RADS; Benign; Calcification; Cancer therapies; Classification; Communications equipment; Diagnostic equipment (Medical); Diagnostic imaging; Diagnostic value; Health aspects; Immunoassay; Laboratories; MTC; Nodules; Papillary thyroid carcinoma; Patients; PTC; Radiology; Radiology, Medical; Thyroid; Thyroid cancer; Thyroid diseases; Ultrasonic imaging; Taiwan; Diagnostic value; MTC; ACR TI-RADS; ACR score; PTC
• ISSN: 1472-6823; 1472-6823
• DOI: 10.1186/s12902-022-01053-z

To evaluate the diagnostic value of American College of Radiology (ACR) score and ACR Thyroid Imaging Report and Data System (TI-RADS) for benign nodules, medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) through comparing with Kwak TI-RADS. Five hundred nine patients diagnosed with PTC, MTC or benign thyroid nodules were included and classified into the benign thyroid nodules group (n = 264), the PTC group (n = 189) and the MTC group (n = 56). The area under the curve (AUC) values were analyzed and the receiver operator characteristic (ROC) curves were drawn to compare the diagnostic efficiencies of ACR score, ACR TI-RADS and KWAK TI-RADS on benign thyroid nodules, MTC and PTC. The AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS for distinguishing malignant nodules from benign nodules were 0.914 (95%CI: 0.886-0.937), 0.871 (95%CI: 0.839-0.899) and 0.885 (95%CI: 0.854-0.911), respectively. In distinguishing of patients with MTC from PTC, the AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS were 0.650 (95%CI: 0.565-0.734), 0.596 (95%CI: 0.527-0.664), and 0.613 (95%CI: 0.545-0.681), respectively. The AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS for the discrimination of patients with MTC, PTC or benign nodules from patients without MTC, PTC or benign nodules were 0.899 (95%CI: 0.882-0.915), 0.865 (95%CI: 0.846-0.885), and 0.873 (95%CI: 0.854-0.893), respectively. The ACR score performed the best, followed ex aequo by the ACR and Kwak TI-RADS in discriminating patients with malignant nodules from benign nodules and patients with MTC from PTC.