Lipid-Protein Interactions in Membranes Containing the Acetylcholine Receptor

Lipid-protein interactions involving the acetylcholine receptor (AChR) from the electric ray Torpedo californica were studied in purified native membrane vesicles and in reconstituted membranes prepared from receptor protein and defined lipids. The effect of AChR on membrane lipids has been examined...

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Bibliographic Details
Published inBiophysical journal Vol. 37; no. 1; pp. 103 - 104
Main Authors McNamee, M.G., Ellena, J.F., Dalziel, A.W.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 1982
Subjects
acetylcholine
E.S.R
lipids
Poster Summaries
reconstitution
Torpedo californica
vesicles
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Summary:Lipid-protein interactions involving the acetylcholine receptor (AChR) from the electric ray Torpedo californica were studied in purified native membrane vesicles and in reconstituted membranes prepared from receptor protein and defined lipids. The effect of AChR on membrane lipids has been examined by electron paramagnetic resonance (EPR) techniques using spin-labeled lipids incorporated into the membranes. Reconstituted membranes were used to study the dependence of AChR function on membrane lipid composition.
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ISSN:0006-3495
1542-0086
DOI:10.1016/S0006-3495(82)84622-5