Traditional Chinese medicine and separation science

• Published in: Journal of separation science Vol. 31; no. 11; pp. 2113 - 2137
• Main Authors: Liu, Shao, Yi, Lun-Zhao, Liang, Yi-Zeng
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley-VCH Verlag 01.06.2008; WILEY-VCH Verlag; WILEY‐VCH Verlag; Wiley
• Subjects: Animals; Biological and medical sciences; chemical analysis; chemical composition; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal - isolation & purification; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; General pharmacology; Humans; isolation techniques; Medical sciences; Medicine, Chinese Traditional; modernization; Oriental traditional medicine; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Review; screening; Separation science; toxicity; Traditional Chinese medicine; Asia; China; Countercurrent chromatography; Chemical analysis; HPLC chromatography; Chromatogram; Review; Medicinal plant; Spectral signature; Sample preparation; Folk medicine; Separation science; Supercritical fluid extraction; Purification; Capillary electrophoresis; Coupled method; Pharmacognosy; Preparative chromatography; Traditional Chinese medicine; Natural compound; Gas chromatography; Authentication; Quality control; Plant origin; Isolation; Mass spectrometry; Chemometrics
• ISSN: 1615-9306; 1615-9314; 1615-9314
• DOI: 10.1002/jssc.200800134

Traditional Chinese medicines (TCMs) are getting more and more popular nowadays in the whole world for improving health condition of human beings as well as preventing and healing diseases. TCM is a multi-component system with components mostly unknown, and only a few compounds are responsible for the pharmaceutical and/or toxic effects. The large numbers of other components in the TCM make the screening and analysis of the bioactive components extremely difficult. So, separation and analysis of the desired chemical components in TCM are very important subjects for modernization research of TCM. Thus, many novel separation techniques with significant advantages over conventional methods were introduced and applied to separation and analysis of the chemical constituents in TCM. This review presents just a brief outline of the applications of different separation methods for the isolation and analysis of TCM constituents.