Best practice in therapeutic drug monitoring

It is the goal of Therapeutic Drug Monitoring (TDM) to use drug concentrations to manage a patient's medication regimen and optimise outcome. Limited resources require that drug assays should only be performed when they do contribute to patient management. For this to be the case a therapeutic...

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Bibliographic Details
Published inBritish journal of clinical pharmacology Vol. 46; no. 2; pp. 95 - 99
Main Author Gross, Annette S.
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Science Ltd 01.08.1998
Blackwell Science
Blackwell Science Inc
Subjects
Biological and medical sciences
clinical interpretation
Drug Monitoring
General pharmacology
Humans
Medical sciences
Original
Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
Pharmacology, Clinical - organization & administration
Pharmacology, Clinical - trends
Pharmacology. Drug treatments
therapeutic drug monitoring
therapeutic management
Human
Therapeutic drug monitoring
Chemotherapy
Treatment
Activity concentration relation
Pharmacokinetics
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Summary:It is the goal of Therapeutic Drug Monitoring (TDM) to use drug concentrations to manage a patient's medication regimen and optimise outcome. Limited resources require that drug assays should only be performed when they do contribute to patient management. For this to be the case a therapeutic drug monitoring service has a far greater role than just therapeutic drug measuring. This article describes the roles and functions of a Best Practice TDM service. The features which can and should be strived for in each step of the TDM process—the decision to request a drug level, the biological sample, the request, laboratory measurement, communication of results by the laboratory, clinical interpretation and therapeutic management—are discussed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0306-5251
1365-2125
DOI:10.1046/j.1365-2125.1998.00770.x