Kinematic and dynamic processes for the control of pointing movements in humans revealed by short-term exposure to microgravity

• Published in: Neuroscience Vol. 135; no. 2; pp. 371 - 383
• Main Authors: Papaxanthis, C., Pozzo, T., McIntyre, J.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 2005; Elsevier
• Subjects: Adult; Arm - physiology; Biological and medical sciences; Biomechanical Phenomena; Fundamental and applied biological sciences. Psychology; gravity force; Gravity Sensing - physiology; Humans; internal models; Male; motor adaptation; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration; motor planning; Movement - physiology; Nonlinear Dynamics; Psychomotor Performance - physiology; Time Factors; Torque; velocity profile; Vertebrates: nervous system and sense organs; Weightlessness; DF; AD; C; velocity profile; motor adaptation; Vpeak; I; DN; RMSD; internal models; L; RMSD el; UF; gravity force; Dev; 1× g; 0× g; MD; UN; TPV; RMSD sh; motor planning; Short term; Human; Goal directed movement; Motor control; Kinematics; Body movement; Models; Planning; Microgravity; Adaptation
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2005.06.063

The generation of accurate motor commands requires implicit knowledge of both limb and environmental dynamics. The action of gravity on moving limb segments must be taken into account within the motor command, and may affect the limb trajectory chosen to accomplish a given motor task. Exactly how the CNS deals with these gravitoinertial forces remains an open question. Does the CNS measure gravitational forces directly, or are they accommodated in the motor plan by way of internal models of physical laws? In this study five male subjects participated. We measured kinematic and dynamic parameters of upward and downward arm movements executed at two different speeds, in both normal Earth gravity and in the weightless conditions of parabolic flight. Exposure to microgravity affected velocity profiles for both directions and speeds. The shape of velocity profiles (the ratio of maximum to mean velocity) and movement duration both showed transient perturbations initially in microgravity, but returned to normal gravity values with practice in 0× g. Differences in relative time to peak velocity between upward versus downward movements, persisted for all trial performed in weightlessness. These differences in kinematic profiles and in the torque profiles used to produce them, diminished, however, with practice in 0× g. These findings lead to the conclusion that the CNS explicitly represents gravitational and inertial forces in the internal models used to generate and execute arm movements. Furthermore, the results suggest that the CNS adapts motor plans to novel environments on different time scales; dynamics adapt first to reproduce standard kinematics, and then kinematics patterns are adapted to optimize dynamics.