The Cambridge MRI database for animal models of Huntington disease

• Published in: NeuroImage (Orlando, Fla.) Vol. 124; no. Pt B; pp. 1260 - 1262
• Main Authors: Sawiak, Stephen J., Morton, A. Jennifer
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2016; Elsevier Limited
• Subjects: Animal models; Animals; Artificial chromosomes; Brain research; Cerebral Cortex - pathology; Cortex; Data processing; Databases, Factual; Datasets; Disease Models, Animal; Genotype & phenotype; Gray Matter - pathology; Humans; Huntington Disease - pathology; Huntingtons disease; Image Processing, Computer-Assisted; Magnetic resonance imaging; Magnetic Resonance Imaging - statistics & numerical data; Medical imaging; Mice; Mouse models; Neuroimaging; R6/2; Sheep models; Studies; Substantia alba; White Matter - pathology; Australia; North America; Europe; R6/2; Mouse models; Sheep models
• ISSN: 1053-8119; 1095-9572
• DOI: 10.1016/j.neuroimage.2015.04.056

We describe the Cambridge animal brain magnetic resonance imaging repository comprising 400 datasets to date from mouse models of Huntington disease. The data include raw images as well as segmented grey and white matter images with maps of cortical thickness. All images and phenotypic data for each subject are freely-available without restriction from (http://www.dspace.cam.ac.uk/handle/1810/243361/). Software and anatomical population templates optimised for animal brain analysis with MRI are also available from this site. •We describe our online database of Huntington's animal images.•400 images to date from mouse models (ex vivo R6/2 of various CAG lengths, YAC128)•12 images to date from sheep models (OVT73 in vivo)