Prospective cohort study of compliance with faecal immunochemical tests for colorectal cancer screening in Hong Kong

• Published in: Preventive medicine Vol. 57; no. 3; pp. 227 - 231
• Main Authors: Wong, Martin C.S., Ching, Jessica Y.L., Lam, Thomas Y.T., Luk, Arthur K.C., Hirai, Hoyee W., Griffiths, Sian M., Chan, Francis K.L., Sung, Joseph J.Y.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.09.2013; Elsevier
• Subjects: Age Factors; Aged; Biological and medical sciences; Chinese people; Colorectal cancer; Colorectal Neoplasms - diagnosis; Compliance; Determinants; Faecal occult blood; Female; Hong Kong; Humans; Immunologic Tests; Internal Medicine; Male; Mass Screening - organization & administration; Medical sciences; Middle Aged; Miscellaneous; Noncompliance; Occult Blood; Patient Compliance; Prevention and actions; Prospective Studies; Public health. Hygiene; Public health. Hygiene-occupational medicine; Screening; Smokers; Socioeconomic Factors; Hong Kong; Asia; China; China, People's Rep., Hong Kong; FIT; Screening; AOR; Compliance; CRC; Colorectal cancer; Determinants; FOBT; Faecal occult blood; Faecal Occult Blood Tests; Faecal Immunochemical Tests; Colorectal Cancer; Adjusted Odds Ratios; Rectal disease; Determinant; Malignant tumor; Medical screening; Blood; Colonic disease; Prospective; Cohort study; Digestive diseases; Intestinal disease; Feces; Public health; Cancer
• ISSN: 0091-7435; 1096-0260; 1096-0260
• DOI: 10.1016/j.ypmed.2013.05.017

This study aims to examine the rate and determinants of faecal immunochemical test (FIT) compliance over a four-year period among asymptomatic participants in a colorectal cancer (CRC) screening programme in Hong Kong. Self-referred screening participants aged between 50 and 70years who chose FIT for annual screening were followed up for four years (2008–2012). All participants were reminded up to three times yearly for FIT retrieval within two months of the expected screening date. The proportions of screening participants who failed to adhere to annual FIT tests in 1, 2, 3 and 4-years, respectively, after the initial screening uptake were evaluated. The factors associated with non-compliance with FITs in any year were assessed by a binary logistic regression analysis. From 5700 consecutive screening participants, the compliance rates to FIT were 95.1%, 79.9%, 66.2% and 68.4% at years one to four, respectively. The proportions of people missing one, two and three tests were 6.2%, 19.6% and 2.1%, respectively. From multivariate regression analysis, male subjects, younger participants, smokers and those with positive family history of CRC were more likely to be non-compliant. Participants identified as at higher risk for screening non-compliance should be especially considered for individual reminders to enhance screening effectiveness. •Faecal test compliance of 5700 colorectal cancer screening participants was studied.•The compliance rates were 95.1%, 79.9%, 66.2% and 68.4% at years 1–4, respectively.•The proportions of people missing 1–3 tests were 6.2%, 19.6% and 2.1%, respectively.•Younger males, smokers and subjects with family history were less compliant.•They should be targeted for more individual reminders to enhance screening uptake.