Ultrastructural Analysis of the Prostate Gland under the Effect of Factors of Chemical Industry

• Published in: Bulletin of experimental biology and medicine Vol. 158; no. 6; pp. 827 - 832
• Main Authors: Nepomnyashchikh, L. M., Lapiy, G. A., Nikityuk, D. B., Neimark, A. I., Kiptilov, A. V., Molodykh, O. P.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2015; Springer; Springer Nature B.V
• Subjects: Adult; Analysis; Biomedical and Life Sciences; Biomedicine; Cell Biology; Chemical industry; Chemical Industry - statistics & numerical data; Collagen; Herbicides; Humans; Internal Medicine; Laboratory Medicine; Male; Middle Aged; Pathology; Pesticides industry; Prostate - drug effects; Prostate - ultrastructure; Prostatitis - chemically induced; Prostatitis - pathology; Sulfuric Acids - toxicity; chronic prostatitis; chemical industry; morphology; ultrastructure; prostate gland
• ISSN: 0007-4888; 1573-8221
• DOI: 10.1007/s10517-015-2872-2

We analyzed ultrastruciture of the cell populations in the prostate gland in chronic nonbacterial prostatitis in a chemical industry worker. It was shown that ultrastructural reorganization of the epithelium consisted in reduction of the secretory compartment of the cytoplasm and dystrophic-degenerative changes in cell organelles. Endothelial cells of the capillaries showed signs of signifi cant degeneration and low intensity of micropinocytosis. Most of the smooth muscle cells underwent dystrophic-degenerative modifi cations of ultrastructural elements. The dominance of degenerative cell changes in the epithelial and stromal cell populations along with intensifi cation of collagen formation in the absence of infl ammatory elements allows us to interpret this pathological condition of the prostate gland as prostate pathology of occupational or mixed genesis.