Reduction in mobility and COVID-19 transmission

• Published in: Nature communications Vol. 12; no. 1; p. 1090
• Main Authors: Nouvellet, Pierre, Bhatia, Sangeeta, Cori, Anne, Ainslie, Kylie E C, Baguelin, Marc, Bhatt, Samir, Boonyasiri, Adhiratha, Brazeau, Nicholas F, Cattarino, Lorenzo, Cooper, Laura V, Coupland, Helen, Cucunuba, Zulma M, Cuomo-Dannenburg, Gina, Dighe, Amy, Djaafara, Bimandra A, Dorigatti, Ilaria, Eales, Oliver D, van Elsland, Sabine L, Nascimento, Fabricia F, FitzJohn, Richard G, Gaythorpe, Katy A M, Geidelberg, Lily, Green, William D, Hamlet, Arran, Hauck, Katharina, Hinsley, Wes, Imai, Natsuko, Jeffrey, Benjamin, Knock, Edward, Laydon, Daniel J, Lees, John A, Mangal, Tara, Mellan, Thomas A, Nedjati-Gilani, Gemma, Parag, Kris V, Pons-Salort, Margarita, Ragonnet-Cronin, Manon, Riley, Steven, Unwin, H Juliette T, Verity, Robert, Vollmer, Michaela A C, Volz, Erik, Walker, Patrick G T, Walters, Caroline E, Wang, Haowei, Watson, Oliver J, Whittaker, Charles, Whittles, Lilith K, Xi, Xiaoyue, Ferguson, Neil M, Donnelly, Christl A
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 17.02.2021; Nature Publishing Group UK; Nature Portfolio
• Subjects: Algorithms; Communicable Disease Control - methods; Communicable Disease Control - statistics & numerical data; Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 - transmission; COVID-19 - virology; Decoupling; Disease control; Disease transmission; Global Health; Humans; Mobility; Models, Theoretical; Pandemics; Pandemics - prevention & control; Physical Distancing; Quarantine - methods; SARS-CoV-2 - isolation & purification; SARS-CoV-2 - physiology; Severe acute respiratory syndrome coronavirus 2; Social distancing
• ISSN: 2041-1723; 2041-1723
• DOI: 10.1038/s41467-021-21358-2

In response to the COVID-19 pandemic, countries have sought to control SARS-CoV-2 transmission by restricting population movement through social distancing interventions, thus reducing the number of contacts. Mobility data represent an important proxy measure of social distancing, and here, we characterise the relationship between transmission and mobility for 52 countries around the world. Transmission significantly decreased with the initial reduction in mobility in 73% of the countries analysed, but we found evidence of decoupling of transmission and mobility following the relaxation of strict control measures for 80% of countries. For the majority of countries, mobility explained a substantial proportion of the variation in transmissibility (median adjusted R-squared: 48%, interquartile range - IQR - across countries [27-77%]). Where a change in the relationship occurred, predictive ability decreased after the relaxation; from a median adjusted R-squared of 74% (IQR across countries [49-91%]) pre-relaxation, to a median adjusted R-squared of 30% (IQR across countries [12-48%]) post-relaxation. In countries with a clear relationship between mobility and transmission both before and after strict control measures were relaxed, mobility was associated with lower transmission rates after control measures were relaxed indicating that the beneficial effects of ongoing social distancing behaviours were substantial.