Reversibility of pancreatic β-cells dysfunction after vitamin D and calcium supplementation: a pilot study in a population of obese and prepubescent North-African children

• Published in: Libyan journal of medicine Vol. 17; no. 1; p. 2059896
• Main Authors: Gaddas, Meriem, Latiri, Imed, Kebaili, Raoudha, Kacem, Ilhem, Jaballah, Nesrine, Maatoug, Jihene, Salaani, Mohamed, Boughammoura, Lamia, Ben Saad, Helmi
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.12.2022; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: Blood Glucose - metabolism; Body mass index; Calcium; Child; Diabetes; Diabetes-mellitus; Dietary Supplements; Drug dosages; Female; Glucose; Hospitals; Humans; Hypotheses; Insulin; insulin production; Insulin Resistance; Laboratories; Male; Obesity; Original; Paediatrics; Pandemics; Parents & parenting; Pediatrics; Physiology; Pilot Projects; Quasi-experimental methods; Tunisia; Vitamin D; Vitamins; Diabetes-mellitus; Tunisia; Paediatrics; obesity; insulin production

The mechanisms of diabetogenesis in children remain largely obscure. This study aimed to determine the impact of vitamin D and calcium supplementation on pancreatic β-cells function in terms of insulin secretion and sensitivity. This was a quasi-experimental study involving 30 obese and prepubescent...