Acceptance and safety of femoral versus radial access for percutaneous coronary intervention (PCI): results from a large monitor-controlled German registry (QuIK)

• Published in: BMC cardiovascular disorders Vol. 22; no. 1; p. 7
• Main Authors: Reifart, Jörg, Göhring, Stefan, Albrecht, Alexander, Haerer, Winfried, Levenson, Benny, Ringwald, Gerd, Gärtner, Patrick, Reifart, Nicolaus
• Format: Journal Article
• Language: English
• Published: England BioMed Central 12.01.2022; BMC
• Subjects: Access site complications; Acute coronary syndromes; Acute myocardial infarction; Aged; Angioplasty; BNK; Cardiology; Cardiovascular disease; Catheterization, Peripheral - methods; Cerebral infarction; Clinical trials; Coronary Angiography - methods; Coronary artery disease; Coronary vessels; Electrocardiography, Ambulatory - methods; Female; Femoral Artery; Femur; Germany - epidemiology; Heart attacks; Heart diseases; Heart surgery; Humans; Intervention; Male; Medical imaging; Monitoring, Physiologic - instrumentation; Myocardial infarction; Patients; Percutaneous coronary intervention; Percutaneous Coronary Intervention - methods; Quality assurance; Quality control; Radial access; Radial Artery; Registries; Retrospective Studies; Success; Germany; Percutaneous coronary intervention; Access site complications; Acute myocardial infarction; Radial access; Coronary artery disease; BNK
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-021-02283-0

In 2015 and 2018, European Society of Cardiology guidelines for percutaneous coronary intervention (PCI) favoring radial access over femoral access were published. These recommendations were based on randomized trials suggesting that patients treated radially experienced reduced bleeding complications and all-cause mortality. We aimed to assess acceptance and results of radial access in a real-world scenario by analyzing all PCI cases in the Quality Assurance in Invasive Cardiology (QuIK) registry. The QuIK registry prospectively collects data on all diagnostic and interventional coronary procedures from 148 private practice cardiology centers in Germany. Major adverse cardiac and cerebrovascular events (MACE) were defined as myocardial infarction, stroke, or death during hospitalization. From 2012 to 2018, 189,917 patients underwent PCI via either access method. The rate of radial approach steadily increased from 13 to 49%. The groups did not differ significantly with respect to age or extent of coronary disease. Femoral approach was significantly more common in patients with ST elevation myocardial infarction and cardiogenic shock. Overall, there were significant differences in MACE (radial 0.12%; femoral 0.24%; p < 0.0009) and access site complications (radial 0.2%; femoral 0.8% (p < 0.0009). Our data reveals an increase in use of radial access in recent years in Germany. The radial approach emerged as favorable regarding MACE in non-myocardial infarction patients, as well as favorable regarding access site complication regardless of indication for percutaneous intervention.