Relative extended haplotype homozygosity signals across breeds reveal dairy and beef specific signatures of selection

• Published in: Genetics selection evolution (Paris) Vol. 47; no. 1; p. 25
• Main Authors: Bomba, Lorenzo, Nicolazzi, Ezequiel L, Milanesi, Marco, Negrini, Riccardo, Mancini, Giordano, Biscarini, Filippo, Stella, Alessandra, Valentini, Alessio, Ajmone-Marsan, Paolo
• Format: Journal Article
• Language: English
• Published: France BioMed Central Ltd 02.04.2015; BioMed Central
• Subjects: Analysis; Animals; Annotations; Beef; Beef cattle; Breeding; Cattle; Cattle - genetics; Chromosomes; Dairying; Datasets; Genes; Genetic aspects; Genomes; Genomics; Genotypes; Haplotypes; Homozygosity; Homozygote; Life Sciences; Linkage disequilibrium; Male; Meat; Meat production; Methods; Milk; Molecular Sequence Annotation; Population; Positive selection; Quality control; Recombination; Selection, Genetic; Signatures

A number of methods are available to scan a genome for selection signatures by evaluating patterns of diversity within and between breeds. Among these, "extended haplotype homozygosity" (EHH) is a reliable approach to detect genome regions under recent selective pressure. The objective of...