Long-term care for people treated for cancer during childhood and adolescence

Worldwide advances in treatment and supportive care for children and adolescents with cancer have resulted in a increasing population of survivors growing into adulthood. Yet, this population is at very high risk of late occurring health problems, including significant morbidity and early mortality....

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Published inThe Lancet (British edition) Vol. 399; no. 10334; pp. 1561 - 1572
Main Authors Tonorezos, Emily S, Cohn, Richard J, Glaser, Adam W, Lewin, Jeremy, Poon, Eileen, Wakefield, Claire E, Oeffinger, Kevin C
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 16.04.2022
Elsevier Limited
Subjects
Adolescent
Adolescents
Adult
Age
Breast cancer
Cancer
Cancer therapies
Cardiomyopathy
Child
Child development
Children
Chronic illnesses
Cognition & reasoning
Cognitive ability
Continuity of care
Delivery of Health Care
Fertility
Health care
Health problems
Health services
Humans
Life expectancy
Long-Term Care
Mammography
Medical diagnosis
Medical personnel
Mental depression
Mental health
Morbidity
Mortality
Neoplasms - therapy
Pediatrics
Population
Population growth
Primary care
Radiation therapy
Support services
Survival
Survivors
Teenagers
Transition to Adult Care
Tumors
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Summary:Worldwide advances in treatment and supportive care for children and adolescents with cancer have resulted in a increasing population of survivors growing into adulthood. Yet, this population is at very high risk of late occurring health problems, including significant morbidity and early mortality. Unique barriers to high-quality care for this group include knowledge gaps among both providers and survivors as well as fragmented health-care delivery during the transition from paediatric to adult care settings. Survivors of childhood and adolescent cancer are at risk for a range of late-occuring side-effects from treatment, including cardiac, endocrine, pulmonary, fertility, renal, psychological, cognitive, and socio-developmental impairments. Care coordination and transition to adult care are substantial challenges, but can be empowering for survivors and improve outcomes, and could be facilitated by clear, effective communication and support for self-management. Resources for adult clinical care teams and primary care providers include late-effects surveillance guidelines and web-based support services.
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Contributors: Conception: EST, KCO; Data collection and interpretation: all authors; Drafting the article: all authors; Critical revision: all authors; Final approval: all authors.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(22)00460-3