A Review on Tetrabromobisphenol A: Human Biomonitoring, Toxicity, Detection and Treatment in the Environment

Tetrabromobisphenol A (TBBPA) is a known endocrine disruptor employed in a range of consumer products and has been predominantly found in different environments through industrial processes and in human samples. In this review, we aimed to summarize published scientific evidence on human biomonitori...

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Published inMolecules (Basel, Switzerland) Vol. 28; no. 6; p. 2505
Main Authors Miao, Baoji, Yakubu, Salome, Zhu, Qingsong, Issaka, Eliasu, Zhang, Yonghui, Adams, Mabruk
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.03.2023
MDPI
Subjects
Bioaccumulation
Biological Monitoring
brominated flame retardant
Chemistry, Analytic
Consumer goods
Contamination
Dust
Endocrine disruptors
Environmental aspects
Flame retardants
Flame Retardants - analysis
Food
Health aspects
human biomonitoring
Humans
Identification and classification
Investigations
Metabolism
Metabolites
Methods
Polybrominated Biphenyls - analysis
Polybrominated Biphenyls - toxicity
Quantitative
Review
tetrabromobisphenol A
toxicity
treatment
China
South Korea
toxicity
treatment
tetrabromobisphenol A
human biomonitoring
brominated flame retardant
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Summary:Tetrabromobisphenol A (TBBPA) is a known endocrine disruptor employed in a range of consumer products and has been predominantly found in different environments through industrial processes and in human samples. In this review, we aimed to summarize published scientific evidence on human biomonitoring, toxic effects and mode of action of TBBPA in humans. Interestingly, an overview of various pretreatment methods, emerging detection methods, and treatment methods was elucidated. Studies on exposure routes in humans, a combination of detection methods, adsorbent-based treatments and degradation of TBBPA are in the preliminary phase and have several limitations. Therefore, in-depth studies on these subjects should be considered to enhance the accurate body load of non-invasive matrix, external exposure levels, optimal design of combined detection techniques, and degrading technology of TBBPA. Overall, this review will improve the scientific comprehension of TBBPA in humans as well as the environment, and the breakthrough for treating waste products containing TBBPA.
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ISSN:1420-3049
1420-3049
DOI:10.3390/molecules28062505