Comparison of Cryptosporidium parvum and Cryptosporidium wrairi by reactivity with monoclonal antibodies and ability to infect severe combined immunodeficient mice

Twenty-three monoclonal antibodies raised to Cryptosporidium parvum and 12 raised to C. wrairi reacted with equal intensity with the heterologous species. Despite demonstration of a close immunologic relationship between these two species, C. wrairi did not induce persistent infection in severe comb...

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Bibliographic Details
Published inInfection and Immunity Vol. 63; no. 1; pp. 360 - 362
Main Authors Chrisp, C.E. (University of Michigan, Ann Arbor, MI.), Mason, P, Perryman, L.E
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.01.1995
Subjects
Animals
Antibodies, Monoclonal
Antibodies, Protozoan - immunology
ANTICORPS MONOCLONAL
ANTICUERPOS MONOCLONALES
Biological and medical sciences
COBAYA
COBAYE
Cross Reactions
Cryptosporidiosis - immunology
CRYPTOSPORIDIUM
Cryptosporidium - immunology
Cryptosporidium - pathogenicity
Cryptosporidium parvum
Cryptosporidium parvum - immunology
Cryptosporidium parvum - pathogenicity
Cryptosporidium wrairi
DEFICIENCE IMMUNOLOGIQUE
DEFICIENCIA INMUNOLOGICA
ETAPAS DEL DESARROLLO ANIMAL
EXPERIMENTACION IN VIVO
Experimental protozoal diseases and models
EXPERIMENTATION IN VIVO
Female
IMMUNOLOGIE
INFECCION EXPERIMENTAL
INFECTION EXPERIMENTALE
Infectious diseases
INMUNOLOGIA
Medical sciences
Mice
Mice, SCID
Parasitic diseases
PODER PATOGENO
POUVOIR PATHOGENE
Protozoal diseases
RATON
REACCION ANTIGENO-ANTICUERPO
REACTION ANTIGENE ANTICORPS
SOURIS
STADE DE DEVELOPPEMENT ANIMAL
TAXONOMIA
TAXONOMIE
Cryptosporidium wrairi
Protozoa
Animal model
Host parasite relation
Protozoal disease
Rodentia
Parasitosis
Monoclonal antibody
Infection
Vertebrata
Experimental disease
Mammalia
Cryptosporidium parvum
Mouse
Severe
Combined immune deficiency
Sporozoa
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Summary:Twenty-three monoclonal antibodies raised to Cryptosporidium parvum and 12 raised to C. wrairi reacted with equal intensity with the heterologous species. Despite demonstration of a close immunologic relationship between these two species, C. wrairi did not induce persistent infection in severe combined immunodeficient mice as did C. parvum
Bibliography:9555949
T10
L72
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ObjectType-Article-1
ObjectType-Feature-2
ISSN:0019-9567
1098-5522
DOI:10.1128/IAI.63.1.360-362.1995