Symptom Management in Metastatic Breast Cancer

• Published in: The oncologist (Dayton, Ohio) Vol. 16; no. 9; pp. 1203 - 1214
• Main Authors: Irvin, William, Muss, Hyman B., Mayer, Deborah K.
• Format: Journal Article
• Language: English
• Published: Durham, NC, USA AlphaMed Press 01.09.2011
• Subjects: Breast Cancer; Breast Neoplasms - pathology; Breast Neoplasms - therapy; Female; Humans; Metastatic breast cancer; Neoplasm Metastasis; Palliative care; Palliative Care - methods; Quality of Life; Symptom management; Treatment
• ISSN: 1083-7159; 1549-490X
• DOI: 10.1634/theoncologist.2011-0159

Approximately 40,000 women die as a result of breast cancer each year and many more live with advanced disease. When breast cancer recurs, the goals of treatment often shift from one of cure to controlling the disease for as long as possible while palliating symptoms interfering with the patient's functional status and quality of life. This requires ongoing discussions with the patient and family about the goals of care. Many symptoms depend on the site of metastasis, with bone being the most frequent, and commonly occur with fatigue, depression, insomnia, and pain. The purpose of this paper is to identify and provide an overview of the management of the most common symptoms in patients with breast cancer metastases. 摘要 每年约4万女性死于乳腺癌，还有更多的乳腺癌患者处于疾病进展期。当乳腺癌复发时，通常情况下，治疗的目标不在于治愈，而是通过缓解那些干预患者功能状态与生活质量的症状来尽可能长时间地控制疾病。在治疗目标上，需要与患者及其家属进行讨论。很多症状取决于转移部位，其中骨转移发生率最高，乳腺癌常见的症状包括乏力、抑郁、失眠以及疼痛。本综述旨在识别并提供转移性乳腺癌患者最常见症状的管理方法。 The most common symptoms in patients with breast cancer metastases are identified and an overview of their management is provided.