Pancreatic β‐cell fate in subjects with COVID‐19

Two recent reports denoted the potential of SARS‐CoV‐2 to directly infect β‐cells and the possible fate of β‐cells under COVID‐19. The fight against SARS‐CoV‐2 will continue to develop more effective therapeutic strategies for diabetes.

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Bibliographic Details
Published inJournal of diabetes investigation Vol. 12; no. 12; pp. 2126 - 2128
Main Author Shirakawa, Jun
Format Journal Article
LanguageEnglish
Published Japan John Wiley & Sons, Inc 01.12.2021
John Wiley and Sons Inc
Wiley
Subjects
Apoptosis
Beta cells
Cell fate
Commentaries
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - metabolism
Diabetes
Diabetes mellitus
Diabetes Mellitus - epidemiology
Diabetes Mellitus - metabolism
Diabetes Mellitus - virology
Disease transmission
eIF-2 kinase
Enzymes
Glucagon
Heparan sulfate
Humans
Immunofluorescence
Infections
Initiation factor eIF-2
Insulin
Insulin-Secreting Cells - metabolism
Insulin-Secreting Cells - virology
Kinases
Pancreas
Pathogenesis
Phosphorylation
Protein kinase R
Proteins
SARS-CoV-2 - metabolism
Severe acute respiratory syndrome coronavirus 2
Signal transduction
Trypsin
Viral infections
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Summary:Two recent reports denoted the potential of SARS‐CoV‐2 to directly infect β‐cells and the possible fate of β‐cells under COVID‐19. The fight against SARS‐CoV‐2 will continue to develop more effective therapeutic strategies for diabetes.
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ISSN:2040-1116
2040-1124
2040-1124
DOI:10.1111/jdi.13671