Application and analysis of retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping for patients with multiple renal tumor: initial experience

• Published in: BMC urology Vol. 17; no. 1; p. 82
• Main Authors: Zhu, Jundong, Jiang, Fan, Li, Pu, Shao, Pengfei, Liang, Chao, Xu, Aiming, Miao, Chenkui, Qin, Chao, Wang, Zengjun, Yin, Changjun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 11.09.2017; BioMed Central; BMC
• Subjects: Adult; Aged; Carcinoma; Care and treatment; Clear cell-type renal cell carcinoma; Constriction; Creatinine; Diagnosis; Feasibility Studies; Female; Humans; Ischemia; Kidney cancer; Kidney neoplasms; Kidney Neoplasms - complications; Kidney Neoplasms - pathology; Kidney Neoplasms - surgery; Kidney transplantation; Laparoscopy; Laparoscopy - methods; Male; Metastases; Methods; Middle Aged; Nephrectomy; Nephrectomy - methods; Partial nephrectomy; Physiological aspects; Renal Artery; Renal function; Renal Insufficiency - complications; Retroperitoneal laparoscopic operation; Retroperitoneal Space; Retrospective Studies; Segmental renal artery; Sequential clamping; Solitary Kidney - complications; Statistical analysis; Surgery; Technical Advance; Tumors; Urology; Veins & arteries; China; Partial nephrectomy; Sequential clamping; Retroperitoneal laparoscopic operation; Segmental renal artery; Kidney neoplasms
• ISSN: 1471-2490; 1471-2490
• DOI: 10.1186/s12894-017-0272-9

To explore the feasibility and safety of retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping for the patients with multiple renal tumor of who have solitary kidney or contralateral kidney insufficiency. Nine patients who have undergone retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping between October 2010 and January 2017 were retrospectively analyzed. Clinical materials and parameters during and after the operation were summarized. Nineteen tumors were resected in nine patients and the operations were all successful. The operation time ranged from 100 to 180 min (125 min); clamping time of segmental renal artery was 10 ~ 30 min (23 min); the amount of blood loss during the operation was 120 ~ 330 ml (190 ml); hospital stay after the operation is 3 ~ 6d (5d). There was no complication during the perioperative period, and the pathology diagnosis after the surgery showed that there were 13 renal clear cell carcinomas, two papillary carcinoma and four perivascular epithelioid cell tumors with negative margins from the 19 tumors. All patients were followed up for 3 ~ 60 months, and no local recurrence or metastasis was detected. At 3-month post-operation follow-up, the mean serum creatinine was 148.6 ± 28.1 μmol/L (p = 0.107), an increase of 3.0 μmol/L from preoperative baseline. For the patients with multiple renal tumors and solitary kidney or contralateral kidney insufficiency, retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping was feasible and safe, which minimized the warm ischemia injury to the kidney and preserved the renal function effectively.