Clinical value of vestibular-evoked myogenic potential tests in patients with sudden sensorineural hearing loss

• Published in: BMC neurology Vol. 19; no. 1; pp. 337 - 6
• Main Authors: Wang, Yuan, Gu, Shun-Tong, Bao, Xiao-Lin, Guo, Jia-Liang
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.12.2019; BioMed Central; BMC
• Subjects: Adult; Asymmetry; Care and treatment; Electrodes; Electromyography; Female; Health screening; Hearing loss; Hearing Loss, Sensorineural - complications; Hearing Loss, Sensorineural - diagnosis; Hearing Tests - methods; Humans; Latency; Male; Middle Aged; Middle ear; Otolaryngology; Patients; Software; Statistical analysis; Sudden sensorineural hearing loss; Vertigo; Vertigo - complications; Vestibular evoked myogenic; Vestibular Evoked Myogenic Potentials; Vestibular nerve; Vestibular system; Japan; Sudden sensorineural hearing loss; Vertigo; Vestibular evoked myogenic
• ISSN: 1471-2377; 1471-2377
• DOI: 10.1186/s12883-019-1576-z

This study aims to investigate the clinical value of two kinds of vestibular-evoked myogenic potentials in patients with sudden sensorineural hearing loss (SSNHL). A total of 82 patients were divided into two groups: vertigo group and non-vertigo group. All patients underwent examinations for pure tone hearing thresholds, middle ear analysis, the videonystagmography, caloric tests, and vestibular-evoked myogenic potentials elicited from the sternocleidomastoid and extraocular muscle. In addition, 30 healthy subjects were selected as the control group. For the 30 healthy subjects, the average latency of p13 and n23 of the cervical vestibular evoked myogenic potentials (cVEMPs) were 13.13 ± 2.89 ms and 23.51 ± 3.25 ms, respectively, and the bilateral amplitude asymmetry rate ranged within 0.05-0.31. The average latency of n10 of the ocular vestibular evoked myogenic potentials (oVEMPs) was 10.13 ± 0.48 ms. The average amplitude of the n10-p15-wave was 5.58 ± 0.65 μV. Among the 35 vertigo patients with SSNHL, 27 patients had normal cVEMP and oVEMP examination results, five patients had abnormal oVEMP examination results, and five patients had abnormal cVEMP examination results. The latency and amplifier of oVEMPs and cVEMPs were within the normal range in 47 SSNHL patients without vertigo. The chi-square value was 5.647, the P-value was equal to 0.017, and the difference was statistically significant at a confidence interval of 95%. OVEMPs and cVEMPs can be used evaluate the vestibular nerve function of SSNHL patients with vertigo.