Thinking forward: promising but unproven ideas for future intensive care

Progress toward determining the true worth of ongoing practices or value of recent innovations can be glacially slow when we insist on following the conventional stepwise scientific pathway. Moreover, a widely accepted but flawed conceptual paradigm often proves difficult to challenge, modify or rej...

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Published inCritical care (London, England) Vol. 23; no. Suppl 1; p. 197
Main Authors Marini, John J, DeBacker, Daniel, Gattinoni, Luciano, Ince, Can, Martin-Loeches, Ignacio, Singer, Pierre, Singer, Mervyn, Westphal, Martin, Vincent, Jean-Louis
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 14.06.2019
BioMed Central
BMC
Subjects
Antibiotics
Ascorbic acid
Clinical trials
Critical care
Critical Care - trends
Critical care medicine
Critical Illness - therapy
Forecasting
Forecasts and trends
Humans
Innovation
Innovations
Intensive care
Lactate
Lithium
Metabolism
Microscopy
Nanotechnology
Organic acids
Paradigm
Post-intensive care syndrome
Proceedings
Sapropterin dihydrochloride
Scientists
Sepsis
Vitamin C
United States
Antibiotic overuse
Subcellular microscopy
Innovation
Ascorbic acid
Paradigm
Lactate
Nutritional support
Lithium
Post-intensive care syndrome
Nanotechnology
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Summary:Progress toward determining the true worth of ongoing practices or value of recent innovations can be glacially slow when we insist on following the conventional stepwise scientific pathway. Moreover, a widely accepted but flawed conceptual paradigm often proves difficult to challenge, modify or reject. Yet, most experienced clinicians, educators and clinical scientists privately entertain untested ideas about how care could or should be improved, even if the supporting evidence base is currently thin or non-existent. This symposium encouraged experts to share such intriguing but unproven concepts, each based upon what the speaker considered a logical but unproven rationale. Such free interchange invited dialog that pointed toward new or neglected lines of research needed to improve care of the critically ill. In this summary of those presentations, a brief background outlines the rationale for each novel and deliberately provocative unconfirmed idea endorsed by the presenter.
Bibliography:ObjectType-Article-1
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ISSN:1364-8535
1466-609X
1364-8535
1366-609X
DOI:10.1186/s13054-019-2462-1