Analysis of Gastric Microbiota by Pyrosequencing: Minor Role of Bacteria Other Than Helicobacter pylori in the Gastric Carcinogenesis

• Published in: Helicobacter (Cambridge, Mass.) Vol. 21; no. 5; pp. 364 - 374
• Main Authors: Jo, Hyun Jin, Kim, Jaeyeon, Kim, Nayoung, Park, Ji Hyun, Nam, Ryoung Hee, Seok, Yeong-Jae, Kim, Yeon-Ran, Kim, Joo Sung, Kim, Jung Mogg, Kim, Jung Min, Lee, Dong Ho, Jung, Hyun Chae
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.10.2016; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Aged, 80 and over; Bacteria; Bacteria - classification; Bacteria - isolation & purification; Bacteria - pathogenicity; Cancer; Carcinogenesis; DNA, Bacterial - chemistry; DNA, Bacterial - genetics; DNA, Ribosomal - chemistry; DNA, Ribosomal - genetics; Female; Follow-Up Studies; Gastric cancer; gastric microbiota; Gastric Mucosa - microbiology; Helicobacter Infections - complications; Helicobacter Infections - microbiology; Helicobacter pylori; Humans; Male; Microbiota; Middle Aged; nitrate-reducing bacteria; nitrosating bacteria; pyrosequencing; RNA, Ribosomal, 16S - genetics; Sequence Analysis, DNA; Stomach Neoplasms - microbiology; nitrate-reducing bacteria; pyrosequencing; nitrosating bacteria; Helicobacter pylori; Gastric cancer; gastric microbiota

Background Little is known about the role of gastric microbiota except for Helicobacter pylori (HP) in human health and disease. We compared the differences of human gastric microbiota according to gastric cancer or control and HP infection status and assessed the role of bacteria other than HP. Met...