The Effect of HIV and the Modifying Effect of Anti-Retroviral Therapy (ART) on Body Mass Index (BMI) and Blood Pressure Levels in Rural South Africa

• Published in: PloS one Vol. 11; no. 8; p. e0158264
• Main Authors: Feigl, Andrea B, Bloom, David E, Danaei, Goodarz, Pillay, Deenan, Salomon, Joshua A, Tanser, Frank, Bärnighausen, Till W
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.08.2016; Public Library of Science (PLoS)
• Subjects: Acquired immune deficiency syndrome; Adipose tissue; Adult; AIDS; Anti-Retroviral Agents - adverse effects; Anti-Retroviral Agents - therapeutic use; Antiretroviral drugs; Biology and Life Sciences; Blood; Blood pressure; Blood Pressure - drug effects; Body mass; Body Mass Index; Body size; Body weight loss; Chronic illnesses; Female; Health risk assessment; Health risks; HIV; HIV - drug effects; HIV - pathogenicity; HIV Infections - complications; HIV Infections - drug therapy; Human immunodeficiency virus; Humans; Lentivirus; Male; Medicine and Health Sciences; Patients; People and places; Population studies; Research and Analysis Methods; Risk analysis; Risk Factors; South Africa; Weight Gain - drug effects; South Africa

High BMI and blood pressure are leading chronic disease risk factors in South Africa. Longterm effects of HIV and ART on adiposity and blood pressure are poorly understood, and direct comparisons of risk factor trajectories in HIV- versus HIV+ populations are rare. In 2003 and 2010, height, weight,...