Type I Interferons Induce Apoptosis by Balancing cFLIP and Caspase-8 Independent of Death Ligands

• Published in: Molecular and Cellular Biology Vol. 33; no. 4; pp. 800 - 814
• Main Authors: Apelbaum, Amir, Yarden, Ganit, Warszawski, Shira, Harari, Daniel, Schreiber, Gideon
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.02.2013; Taylor & Francis
• Subjects: Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein - genetics; CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism; Caspase 8 - genetics; Caspase 8 - metabolism; Cell Cycle Checkpoints; Cell Line, Tumor; Enzyme Activation; Gene Expression Regulation; Humans; Interferon Type I - metabolism; Interferon-gamma - metabolism; Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics; Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism; RNA Interference; RNA, Small Interfering - genetics
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.01430-12

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