Anticonvulsant Hypersensitivity Syndrome Treated With Intravenous Immunoglobulin

Anticonvulsant hypersensitivity syndrome is a severe, potentially life-threatening, reaction to the aromatic anticonvulsant medications. Reported here is a case of anticonvulsant hypersensitivity syndrome secondary to phenobarbital in a 2-year-old boy; he responded to drug withdrawal, corticosteroid...

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Bibliographic Details
Published inPediatric neurology Vol. 43; no. 1; pp. 65 - 69
Main Authors Dredge, David C., Parsons, Elizabeth C., Carter, Lindsay P., Staley, Kevin J.
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.07.2010
Elsevier
Subjects
Biological and medical sciences
Child, Preschool
Drug Hypersensitivity - therapy
Humans
Immunoglobulins, Intravenous - therapeutic use
Male
Malformations of the nervous system
Medical sciences
Neurology
Pediatrics
Phenobarbital - adverse effects
Treatment Outcome
Immunoglobulins
Nervous system diseases
Anticonvulsant
Treatment
Intravenous administration
Hypersensitivity
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Summary:Anticonvulsant hypersensitivity syndrome is a severe, potentially life-threatening, reaction to the aromatic anticonvulsant medications. Reported here is a case of anticonvulsant hypersensitivity syndrome secondary to phenobarbital in a 2-year-old boy; he responded to drug withdrawal, corticosteroids, and intravenous immunoglobulin. The literature regarding treatment of this syndrome is reviewed.
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ISSN:0887-8994
1873-5150
1873-5150
DOI:10.1016/j.pediatrneurol.2010.03.010