Comparative study of ultrasound-guided paravertebral block versus intravenous tramadol for postoperative pain control in percutaneous nephrolithotomy

• Published in: BMC anesthesiology Vol. 18; no. 1; p. 24
• Main Authors: Hatipoglu, Zehra, Gulec, Ersel, Turktan, Mediha, Izol, Volkan, Arıdogan, Atilla, Gunes, Yasemin, Ozcengiz, Dilek
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.02.2018; BioMed Central; BMC
• Subjects: Adult; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - therapeutic use; Comparative analysis; Complications and side effects; Drug therapy; Female; Humans; Male; Nephrolithotomy, Percutaneous; Nerve Block - methods; Pain management; Pain, Postoperative - drug therapy; Paravertebral block; Patient outcomes; Percutaneous nephrostomy; Postoperative analgesia; Postoperative pain; Prospective Studies; Tramadol; Tramadol - administration & dosage; Tramadol - therapeutic use; Treatment Outcome; Ultrasonography, Interventional - methods; Paravertebral block; Postoperative analgesia; Tramadol
• ISSN: 1471-2253; 1471-2253
• DOI: 10.1186/s12871-018-0479-7

Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure for renal calculi, and nephrostomy tubes lead to postoperative pain after PCNL. Regional techniques (e.g., epidural analgesia and peripheral blocks) and opioids are applied for postoperative pain treatment. The aim of this study was to compare effectiveness of ultrasound-guided paravertebral block (PVB) and tramadol on postoperative pain in patients who underwent PCNL. Fifty-three patients were included in this prospective randomized study. The patients were allocated into two groups: the PVB group (group P, n = 26) and the tramadol group (group T, n = 27). All patients were administered standard general anaesthesia. Ultrasound-guided PVB was performed at the T11- L1 levels using 0.5% bupivacaine for a total dose of 15 mL in group P. Patients in group T were intravenously administered a loading dose of 1 mg/kg tramadol. Patients in both groups were given patient-controlled analgesia. Haemodynamic parameters, visual analogue scale (VAS) scores, side effects, and complications, tramadol consumption and additional analgesic requirements of the patients were recorded after surgery. Haemodynamic parameters were statistically similar between the groups. The VAS in group P were statistically lower than in group T. In the 24-h period after surgery, total PCA tramadol consumption was statistically lower in group P than in group T. The use of supplemental analgesic in group T was higher than in group P. Ultrasound-guided PVB was found to be an effective analgesia compared to tramadol, and no additional complications were encountered. ClinicalTrials.gov, NCT02412930 , date of registration: March 27, 2015, retrospectively registered.