Potential Application of Pulsed Field Ablation in Ventricular Arrhythmias

• Published in: Medicina (Kaunas, Lithuania) Vol. 59; no. 4; p. 723
• Main Authors: Qiu, Jie, Dai, Meiyan, Bai, Yang, Chen, Guangzhi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2023; MDPI
• Subjects: Ablation; Ablation (Surgery); Atrial Fibrillation; Cardiac arrhythmia; Cardiomyocytes; Care and treatment; Catheter Ablation - methods; Catheters; coronary venous system; Coronary vessels; Electric fields; Electrodes; Heart Ventricles - surgery; Humans; Methods; Muscle contraction; myocardium; Permeability; pulsed field ablation; Purkinje system; Review; Tachycardia, Ventricular - surgery; Treatment Outcome; ventricular arrhythmias; Ventricular fibrillation; Ventricular Premature Complexes - surgery; China; coronary venous system; Purkinje system; myocardium; pulsed field ablation; ventricular arrhythmias
• ISSN: 1648-9144; 1010-660X; 1648-9144
• DOI: 10.3390/medicina59040723

Pulsed field ablation (PFA) is a new ablative method for the therapy of arrhythmia. Recent preclinical and clinical studies have already demonstrated the feasibility and safety of PFA for the treatment of atrial fibrillation (AF). However, the application of PFA may not be limited to the above fields. There are some data on the application of PFA on ventricular arrhythmias (VAs), such as ventricular fibrillation (VF) and ventricular tachycardia (VT). Further, a case report about PFA has been published recently, in which PFA was successfully applied to the ablation of premature ventricular contractions (PVCs) from the right ventricular outflow tract. Thus, we aimed to review recent research findings of PFA in ventricular ablation and evaluate the possibility of its application in VAs.