Breath-hold High-resolution T1-weighted Gradient Echo Liver MR Imaging with Compressed Sensing Obtained during the Gadoxetic Acid-enhanced Hepatobiliary Phase: Image Quality and Lesion Visibility Compared with a Standard T1-weighted Sequence

• Published in: Magnetic Resonance in Medical Sciences Vol. 23; no. 2; pp. 146 - 152
• Main Authors: Ihara, Kenichiro, Onoda, Hideko, Tanabe, Masahiro, Iida, Etsushi, Ueda, Takaaki, Kobayashi, Taiga, Higashi, Mayumi, Nickel, Marcel Dominik, Imai, Hiroshi, Ito, Katsuyoshi
• Format: Journal Article
• Language: English
• Published: Japan Japanese Society for Magnetic Resonance in Medicine 01.01.2024; Japan Science and Technology Agency
• Subjects: Bile ducts; compressed sensing; Conspicuity; gadolinium ethoxybenzyl diethlenetriamine pentaacetic acid; hepatobiliary phase; High resolution; Image acquisition; Image contrast; Image enhancement; Image processing; Image quality; Image reconstruction; Image resolution; Lesions; Liver; Magnetic resonance imaging; Major Paper; Medical imaging; Sharpness; Signal quality; Vessels; hepatobiliary phase; magnetic resonance imaging; compressed sensing; gadolinium ethoxybenzyl diethlenetriamine pentaacetic acid
• ISSN: 1347-3182; 1880-2206
• DOI: 10.2463/mrms.mp.2022-0137

Purpose: To evaluate the feasibility of breath-hold (BH) high-resolution (HR) T1-weighted gradient echo hepatobiliary phase (HBP) imaging using compressed sensing (CS) in gadoxetic acid-enhanced liver MRI in comparison with standard HBP imaging using parallel imaging (PI).Methods: The study included 122 patients with liver tumors with hypointensity in the HBP who underwent both HR HBP imaging with CS and standard HBP imaging with PI. Two radiologists evaluated the liver edge sharpness, hepatic vessel conspicuity, bile duct conspicuity, image noise, and overall image quality, as well as the lesion conspicuity on HR and standard HBP imaging and the contrast-enhanced (CE) MR cholangiography (MRC) image quality reconstructed from HBP images. As a quantitative analysis, the SNR of the liver and the liver to lesion signal intensity ratio (LLSIR) were also determined.Results: The liver edge sharpness, hepatic vessel conspicuity, bile duct conspicuity, and overall image quality as well as the lesion conspicuity and the LLSIR on HR HBP imaging with CS were significantly higher than those on standard HBP imaging (all of P < 0.001). The image quality of CE-MRC reconstructed from HR HBP imaging with CS was also significantly higher than that from standard HBP imaging (P < 0.001). Conversely, the SNR of liver in standard HBP was significantly higher than that in HR HBP with CS (P < 0.001).Conclusion: BH HR HBP imaging with CS provided an improved overall image quality, lesion conspicuity, and CE-MRC visualization when compared with standard HBP imaging without extending the acquisition time.