A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing

A review of the human developmental neuroimaging literature that investigates outcomes following exposure to psychosocial adversity is presented with a focus on two subcortical structures - the hippocampus and the amygdala. Throughout this review, we discuss how a consideration of developmental timi...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in human neuroscience Vol. 3; p. 68
Main Author Tottenham, Nim
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Research Foundation 2009
Frontiers Media S.A
Subjects
adversity
Age
Amygdala
Brain research
development
Expression
Hippocampus
human
Medical imaging
Mental disorders
Mental health care
Neuroimaging
Neuroscience
Reviews
Stress
Studies
Los Angeles California
United States > US
stress
amygdala
HPA axis
adversity
hippocampus
human development
Online AccessGet full text

Cover

More Information
Summary:A review of the human developmental neuroimaging literature that investigates outcomes following exposure to psychosocial adversity is presented with a focus on two subcortical structures - the hippocampus and the amygdala. Throughout this review, we discuss how a consideration of developmental timing of adverse experiences and age at measurement might provide insight into the seemingly discrepant findings across studies. We use findings from animal studies to suggest some mechanisms through which timing of experiences may result in differences across time and studies. The literature suggests that early life may be a time of heightened susceptibility to environmental stressors, but that expression of these effects will vary by age at measurement.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
Edited by: Elizabeth D. O'Hare, University of California at Berkeley, USA
Reviewed by: Amanda Guyer, University of California, USA; Eric Nelson, National Institute of Mental Health, USA
ISSN:1662-5161
1662-5161
DOI:10.3389/neuro.09.068.2009