Early Identification and Intervention in Pediatric Obsessive-Compulsive Disorder

• Published in: Brain sciences Vol. 13; no. 3; p. 399
• Main Authors: Liu, Xingyu, Fan, Qing
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25.02.2023; MDPI
• Subjects: Adults; Biomarkers; Brain research; Child psychopathology; Development and progression; Disease prevention; early identification; Early intervention; Epigenetics; Etiology; Genomes; Inflammation; Medical imaging; Medical research; Mental disorders; Neurobiology; Neuroimaging; Neuroses; Obsessive compulsive disorder; pediatric obsessive-compulsive disorder; Pediatrics; prevention; Prognosis; Review; Teenagers; Youth; United Kingdom; pediatric obsessive-compulsive disorder; early intervention; early identification; prevention
• ISSN: 2076-3425; 2076-3425
• DOI: 10.3390/brainsci13030399

Obsessive-compulsive disorder (OCD) is a psychiatric disorder characterized by persistent thoughts with subsequent repetitive behaviors. Interventions that are effective for adult OCD cannot simply be generalized to pediatric OCD, since OCD in children and adolescents usually has a different clinical presentation, etiology and course from adult OCD. Delayed and inadequate treatment is associated with a worse prognosis, making the need for early identification and intervention in pediatric OCD very urgent. In this paper, we reflected on the current constraints that make early interventions for pediatric OCD unpromoted and reviewed the approaches with potential application for early identification and early intervention in pediatric OCD, categorized by three-level prevention stages corresponding to a clinical staging model. Since the etiology of pediatric OCD is still unclear, primary prevention is most lacking, and early interventions for pediatric OCD are currently focused on the secondary prevention stage, which aims to prevent the conversion of obsessive-compulsive symptoms into full-blown OCD; tertiary prevention mostly focuses on the alleviation of mild to moderate OCD, while interventions for co-morbidities are still in their infancy. We closed by considering the important research questions on this topic.