Community-associated methicillin-resistant Staphylococcus aureus necrotizing pneumonia in a healthy neonate

• Published in: Journal of microbiology, immunology and infection Vol. 47; no. 6; pp. 555 - 557
• Main Authors: Lim, Wai Ho, Lien, Reyin, Huang, Yhu-Chering, Lee, Wen Jen, Lai, Jing Yao
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.12.2014
• Subjects: Anti-Bacterial Agents - therapeutic use; Community-Acquired Infections - diagnosis; Community-Acquired Infections - microbiology; Community-Acquired Infections - pathology; Community-Acquired Infections - therapy; Community-associated methicillin-resistant Staphylococcus aureus; Empyema - diagnosis; Empyema - etiology; Empyema - pathology; Female; Humans; Infant, Newborn; Infectious Disease; Lung - pathology; Medical Education; Methicillin-Resistant Staphylococcus aureus - isolation & purification; Necrosis - pathology; Neonate; Pneumonectomy; Pneumonia; Pneumonia, Staphylococcal - complications; Pneumonia, Staphylococcal - diagnosis; Pneumonia, Staphylococcal - microbiology; Pneumonia, Staphylococcal - pathology; Respiratory syncytial virus; Respiratory Syncytial Virus Infections - diagnosis; Respiratory Syncytial Virus Infections - pathology; Staphylococcus aureus; Vancomycin - therapeutic use; Community-associated methicillin-resistant Staphylococcus aureus; Pneumonia; Neonate
• ISSN: 1684-1182; 1995-9133
• DOI: 10.1016/j.jmii.2012.07.001

The number of cases of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia has increased since the late 1990s, with skin and soft tissue infections predominant among neonates. Herein, we present a rare case of CA-MRSA necrotizing pneumonia with empyema following respiratory syncytial virus (RSV) infection in a healthy neonate. Despite prompt vancomycin treatment, the disease worsened and finally we had to perform pneumonectomy. This case highlights the possibility of emerging CA-MRSA-related invasive disease among neonates.