Malassezia globosa tends to grow actively in summer conditions more than other cutaneous Malassezia species

• Published in: Journal of dermatology Vol. 39; no. 7; pp. 613 - 616
• Main Authors: AKAZA, Narifumi, AKAMATSU, Hirohiko, TAKEOKA, Shiori, SASAKI, Yasuyuki, MIZUTANI, Hiroshi, NAKATA, Satoru, MATSUNAGA, Kayoko
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.07.2012; Wiley Subscription Services, Inc
• Subjects: Dermatomycoses - etiology; Dermatomycoses - microbiology; fatty acid; Fatty Acids, Nonesterified - pharmacology; Humans; lipase; Lipase - metabolism; Malassezia; Malassezia - drug effects; Malassezia - enzymology; Malassezia - growth & development; Malassezia - pathogenicity; Malassezia globosa; Seasons; Species Specificity; sweat; Sweat - chemistry; Sweat - microbiology; Temperature
• ISSN: 0385-2407; 1346-8138; 1346-8138
• DOI: 10.1111/j.1346-8138.2011.01477.x

Malassezia globosa is a major pathogen of Malassezia folliculitis (MF) and the predominant species on human skin. The aim of this study was to clarify the differences between M. globosa and other cutaneous Malassezia species, M. restricta, M. dermatis, M. sympodialis and M. furfur. The optimum growth temperature, effects of compounds of sweat and free fatty acids on growth, and lipase activities of five cutaneous Malassezia species were determined. The growth of M. globosa was promoted strongly by the compounds of sweat and high temperature unlike that of other cutaneous Malassezia species. This result clarified that M. globosa tended to grow actively in summer conditions more than other cutaneous Malassezia species. Furthermore, M. globosa showed high lipase activity. We consider these characteristics of M. globosa to relate to the pathogenesis of MF.