Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis

The aim of this study was to investigate the capacity of strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both sessile and planktonic forms. Only non-typeable isolates of were correlated with a greater biofilm formation capacity. The MC...

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Published inPolish journal of microbiology Vol. 65; no. 1; pp. 105 - 109
Main Authors ESPINOSA, IVETTE, BÁEZ, MICHEL, LOBO, EVELYN, MARTÍNEZ, SIOMARA, GOTTSCHALK, MARCELO
Format Journal Article
LanguageEnglish
Published Poland Sciendo 01.01.2016
Exeley Inc
De Gruyter Poland
Subjects
Acetylcysteine - pharmacology
Anti-Bacterial Agents - pharmacology
Antibiotics
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Bacteria
biofilm
Biofilms
Biofilms - drug effects
Biofilms - growth & development
Hogs
Infections
Laboratories
N-acetylcystein
Penicillin
Penicillin G
Penicillin G - pharmacology
Pneumonia
Streptococcus suis
Streptococcus suis - drug effects
Streptococcus suis - physiology
Cuba
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Summary:The aim of this study was to investigate the capacity of strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both sessile and planktonic forms. Only non-typeable isolates of were correlated with a greater biofilm formation capacity. The MCI of Penicillin G and NAC required for inhibiting biofilm growth were higher than the required concentration for inhibiting planktonic growth. The combinations of NAC and Penicillin G showed a strong synergistic activity that inhibited biofilm formation and disrupted the pre-formed biofilm of
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ISSN:2544-4646
1733-1331
2544-4646
DOI:10.5604/17331331.1197282