Differential Processing of Objects under Various Viewing Conditions in the Human Lateral Occipital Complex

The invariant properties of human cortical neurons cannot be studied directly by fMRI due to its limited spatial resolution. Here, we circumvented this limitation by using fMR adaptation, namely, reduction of the fMR signal due to repeated presentation of identical images. Object-selective regions (...

Full description

Saved in:
Bibliographic Details
Published inNeuron (Cambridge, Mass.) Vol. 24; no. 1; pp. 187 - 203
Main Authors Grill-Spector, Kalanit, Kushnir, Tammar, Edelman, Shimon, Avidan, Galia, Itzchak, Yacov, Malach, Rafael
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.09.1999
Subjects
Adaptation, Physiological
Adult
Automobiles
Face
Female
Humans
Light
Magnetic Resonance Imaging
Male
Middle Aged
Occipital Lobe - physiology
Rotation
Time Factors
Visual Perception - physiology
Online AccessGet full text

Cover

More Information
Summary:The invariant properties of human cortical neurons cannot be studied directly by fMRI due to its limited spatial resolution. Here, we circumvented this limitation by using fMR adaptation, namely, reduction of the fMR signal due to repeated presentation of identical images. Object-selective regions (lateral occipital complex [LOC]) showed a monotonic signal decrease as repetition frequency increased. The invariant properties of fMR adaptation were studied by presenting the same object in different viewing conditions. LOC exhibited stronger fMR adaptation to changes in size and position (more invariance) compared to illumination and viewpoint. The effect revealed two putative subdivisions within LOC: caudal–dorsal (LO), which exhibited substantial recovery from adaptation under all transformations, and posterior fusiform (PF/LOa), which displayed stronger adaptation. This study demonstrates the utility of fMR adaptation for revealing functional characteristics of neurons in fMRI studies.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:0896-6273
1097-4199
DOI:10.1016/S0896-6273(00)80832-6