Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute–Working Group 1996 guidelines

Standardized criteria for diagnosis and response assessment are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. Therefore, a National Cancer Institute–sponsored Working Group (NCI-WG) on chronic lymphocytic leukemia (CLL) published g...

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Bibliographic Details
Published inBlood Vol. 111; no. 12; pp. 5446 - 5456
Main Authors Hallek, Michael, Cheson, Bruce D., Catovsky, Daniel, Caligaris-Cappio, Federico, Dighiero, Guillaume, Döhner, Hartmut, Hillmen, Peter, Keating, Michael J., Montserrat, Emili, Rai, Kanti R., Kipps, Thomas J.
Format Journal Article
LanguageEnglish
Published Washington, DC Elsevier Inc 15.06.2008
The Americain Society of Hematology
American Society of Hematology
SeriesReview Article
Subjects
Biological and medical sciences
Clinical Trials as Topic - standards
Education
Hematologic and hematopoietic diseases
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell - therapy
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
National Cancer Institute (U.S.) - standards
Review
United States
United States
Chronic lymphocytic leukemia
Treatment
Hematology
Lymphoproliferative syndrome
Updating
Malignant hemopathy
Workshop
Diagnosis
Recommendation
Cancer
International
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Summary:Standardized criteria for diagnosis and response assessment are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. Therefore, a National Cancer Institute–sponsored Working Group (NCI-WG) on chronic lymphocytic leukemia (CLL) published guidelines for the design and conduct of clinical trials for patients with CLL in 1988, which were updated in 1996. During the past decade, considerable progress has been achieved in defining new prognostic markers, diagnostic parameters, and treatment options. This prompted the International Workshop on Chronic Lymphocytic Leukemia (IWCLL) to provide updated recommendations for the management of CLL in clinical trials and general practice.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
content type line 23
ObjectType-Instructional Material/Guideline-4
ISSN:0006-4971
1528-0020
1528-0020
DOI:10.1182/blood-2007-06-093906