Luteolin enhances oxidative stress tolerance via the daf-16 pathway in the nematode Caenorhabditis elegans

• Published in: Food Science and Technology Research Vol. 30; no. 2; pp. 253 - 260
• Main Authors: Yamamoto, Ryoko, Takahashi, Eriko, Harada, Maho, Sawahata, Izumi, Nishizuka, Makoto
• Format: Journal Article
• Language: English
• Published: Tsukuba Japanese Society for Food Science and Technology 01.01.2024; Japan Science and Technology Agency
• Subjects: Caenorhabditis elegans; Cytotoxicity; daf-16; Gene expression; Life span; lifespan; luteolin; Lymphocytes T; MnSOD gene; Oxidative stress; Prolongation; Sod; Worms

Luteolin, widely present in plants, has various physiological functions. Here, we aimed to investigate whether luteolin affects lifespan and oxidative stress tolerance using Caenorhabditis elegans. Luteolin had no effect on the lifespan of wild-type N2 worms under normal conditions. In contrast, lut...