Anti-helminthic drugs in recurrent apthous stomatitis: A short review

Recurrent aphthous stomatitis (RAS) is a common mucosal condition producing painful ulcerations in the oral cavity and considerable clinical morbidity. The etiology remains obscure, though local trauma, psychologic stress, hematinic deficiencies and immune dysregulation have been implicated. Though...

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Published inJournal of pharmacy & bioallied science Vol. 6; no. 2; pp. 65 - 68
Main Authors Sharma, Shilpa, Ali, Fareedi Mukram, Saraf, Kedar, Mudhol, Anupama
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.04.2014
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Anthelmintics
Anti-helminthic drugs
Disease
Dosage and administration
Drug therapy
Immune system
levamisole
Pain
Patients
recurrent apthous stomatitis
Review
Stomatitis
Viral infections
levamisole
recurrent apthous stomatitis
Anti-helminthic drugs
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Summary:Recurrent aphthous stomatitis (RAS) is a common mucosal condition producing painful ulcerations in the oral cavity and considerable clinical morbidity. The etiology remains obscure, though local trauma, psychologic stress, hematinic deficiencies and immune dysregulation have been implicated. Though the primary goals of therapy are symptomatic relief of pain, the clinicians are aiming toward reducing the frequency, duration, number of ulcerations and increasing ulcer free periods with systemic drug therapy if topical medications appear ineffective. Levamisole, an antihelminthic drug has been tried with promising results in patients with severe RAS providing long-term benefits.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0976-4879
0975-7406
0975-7406
DOI:10.4103/0975-7406.129169