Clinicopathologic and Cytogenetic Analyses of Three Cases of Primary Uterine Non-Hodgkin's Lymphoma

• Published in: Internal Medicine Vol. 40; no. 10; pp. 1028 - 1031
• Main Authors: KANEKO, Hiroto, KITA, Yuri, TANIWAKI, Masafumi, KASHIMA, Kei, OHKAWARA, Yasuo
• Format: Journal Article
• Language: English
• Published: Tokyo The Japanese Society of Internal Medicine 01.10.2001; Japanese Society of Internal Medicine
• Subjects: Aged; Biological and medical sciences; Female; Female genital diseases; Gynecology. Andrology. Obstetrics; Hematologic and hematopoietic diseases; Humans; karyotype; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Lymphoma, B-Cell - genetics; Lymphoma, B-Cell - pathology; Medical sciences; Middle Aged; NHL; Severity of Illness Index; Tumors; Uterine Neoplasms - genetics; Uterine Neoplasms - pathology; uterus; Case study; Human; Uterus; Lymphoproliferative syndrome; Uterine diseases; Cytogenetics; Female; Malignant hemopathy; Non Hodgkin lymphoma; Karyotype; Female genital diseases
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.40.1028

Primary uterine non-Hodgkin's lymphoma (NHL) is an extremely rare disease. To accumulate more information on clinical data, we report three cases of primary uterine NHL with apparently the first demonstration of karyotypic analysis. Histological diagnosis was diffuse large B cell type in all patients. Two of them with advanced stage showed chemoresistance and a short survival. The remaining case with early stage showed an uneventful course following operation. No common chromosomal abnormality was detected. The therapeutic strategy for uterine NHL might therefore be similar to that for other types of aggressive NHL, although a larger study is needed. (Internal Medicine 40: 1028-1031, 2001)