An unusual initial presentation of hepatocellular carcinoma as a sellar mass

Sellar masses are frequently adenomatous pituitary tumors. Metastatic disease is unusual, often mimicking the presentations of adenomas. Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy but unusual to have a pituitary metastasis (PM). A 65-year-old man presented with head...

Full description

Saved in:
Bibliographic Details
Published inJournal of natural science, biology and medicine Vol. 6; no. 2; pp. 471 - 474
Main Authors Shah, Nihar, Cavanagh, Yana, Shaaban, Hamid, Stein, Beth, Shaikh, Sohail, Kaswala, Dharmesh, Baddoura, Walid
Format Journal Article
LanguageEnglish
Published India Medknow Publications Pvt Ltd 01.07.2015
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Subjects
Care and treatment
Case Report
Case studies
Diagnosis
Hepatocellular carcinoma
pituitary gland
metastasis
Hepatocellular carcinoma
Online AccessGet full text

Cover

More Information
Summary:Sellar masses are frequently adenomatous pituitary tumors. Metastatic disease is unusual, often mimicking the presentations of adenomas. Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy but unusual to have a pituitary metastasis (PM). A 65-year-old man presented with headache, diplopia, ptosis, decreased vision in the right eye and unintentional weight loss of 32lbs. Preliminary out-patient work-up revealed a mass in the pituitary region. Cranial imaging showed 3.1 cm × 3.2 cm × 4.4 cm lesion. Abdominal imaging (computed tomography and magnetic resonance imaging) demonstrated a lobulated, nodular and heterogeneous right lobe of the liver. Trans-sphenoidal resection of the sellar mass favored metastatic HCC on histology. Liver biopsy confirmed HCC. We recommend maintaining an increased clinical suspicion upon evaluation of nonclassical clinical and radiological presentations of suspected PM/malignancy; as well as pursuing additional investigations in all early cases.
ISSN:0976-9668
2229-7707
DOI:10.4103/0976-9668.160045