Particle Sizes and Antibacterial Activity of Radix Astragalus and Radix Isatidis Ultrafine Powders

• Published in: Agricultural biotechnology (Pawtucket, R.I.) Vol. 5; no. 4; pp. 42 - 45
• Main Authors: Shi, Qiumei, Shao, Xinhua, Wang, Xiumin, Meng, Xia, Hou, Xiaoqiao, Yang, Baoxin, Guo, Leiyu, Gao, Jinglong
• Format: Journal Article
• Language: English
• Published: Cranston Wu Chu (USA-China) Science and Culture Media Corporation 01.08.2016
• Subjects: 抗菌活性; 板蓝根; 激光粒度分析仪; 粒径; 超微粉体; 超细粉体; 鸡源大肠杆菌; 黄芪
• ISSN: 2164-4993

Using 9200 laser particle size analyzer and KYKY-2800 scanning electron microscope, particle sizes and cellular morphology of Radix Astragalus and Radix Isatidis ultrafine powders were observed. According to the results, the particle size of 89. 1 % of Radix Astragalus ultrafine powders ranged from 1.729 [xm to 44.938 ｜xm, Z ）50 =4.368 ｜xm; the particle size of 93.411% of Radix Isatidis ultrafine powders ranged from 1.510 [xm to 44.938 ｜xm, Z ）50 = 8 .7 2 6 [xm. Radix As-tragalus and Radix Isatidis ultrafine powders were pulverized completely without intact cellular morphology. The antibacterial activity of Radix Astragalus and Radix Isatidis ultrafine powders against chicken-derived E. coli （078） was investigated. The results indicated that Radix Astragalus and Radix Isatidis ultrafine powders exhibited higher antibacterial activity against chicken-derived E. coli （078 ） compared with the corresponding coarse powders. This study laid a solid foundation for the development and application of Chinese medicine ultrafine powder preparations.