A Double-Blind, Randomized, Placebo-Controlled Trial of Divalproex Extended-Release in the Treatment of Bipolar Disorder in Children and Adolescents
A double-blind study that involves 150 patients aged 10-17 on the effect of divalproex extended-release in the treatment of bipolar disorder shows that the drug was similar to placebo based on adverse events and that no treatment effect was observed in the drug. The drug is not suitable for treatmen...
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Published in | Journal of the American Academy of Child and Adolescent Psychiatry Vol. 48; no. 5; pp. 519 - 532 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Lippincott Williams & Wilkins
01.05.2009
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Subjects | |
Online Access | Get more information |
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Summary: | A double-blind study that involves 150 patients aged 10-17 on the effect of divalproex extended-release in the treatment of bipolar disorder shows that the drug was similar to placebo based on adverse events and that no treatment effect was observed in the drug. The drug is not suitable for treatment of youths with bipolar I disorder, mixed or manic state. |
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ISSN: | 0890-8567 1527-5418 |
DOI: | 10.1097/CHI.0b013e31819c55ec |