Comparison of the incidence and visual significance of posterior capsule opacification between multifocal spherical, monofocal spherical, and monofocal aspheric intraocular lenses

• Published in: Journal of cataract and refractive surgery Vol. 35; no. 7; pp. 1234 - 1238
• Main Authors: Biber, Joseph M., Sandoval, Helga P., Trivedi, Rupal H., Fernández de Castro, Luis E., French, John W., Solomon, Kerry D.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2009; Elsevier
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Cataract - etiology; Cataract - therapy; Female; Follow-Up Studies; Humans; Incidence; Laser Therapy; Lasers, Solid-State - therapeutic use; Lens Capsule, Crystalline - pathology; Lens Capsule, Crystalline - surgery; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Medical sciences; Middle Aged; Ophthalmology; Phacoemulsification; Postoperative Complications; Pseudophakia - physiopathology; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the eye and orbit; Visual Acuity - physiology; Opacification; Treatment; Surgery; Posterior; Capsule; Ophthalmology; Intraocular lens; Comparative study; Incidence
• ISSN: 0886-3350; 1873-4502; 1873-4502
• DOI: 10.1016/j.jcrs.2009.03.013

To determine and compare the incidence of posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) laser capsulotomy after implantation of 3 intraocular lens types (IOLs). Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. This retrospective chart review comprised eyes having uneventful phacoemulsification and implantation of 1 of 3 AcrySof IOLs: ReSTOR SN60D3 (multifocal spherical group), Natural SN60AT (monofocal spherical group), or IQ SN60WF (monofocal aspheric group). Eyes were matched by age, sex, and follow-up. The PCO rate, Nd:YAG capsulotomy rate, time from surgery to PCO diagnosis, and time from surgery to Nd:YAG capsulotomy were assessed. Charts of 225 eyes (75 in each group) with a mean follow-up of 15.9 months ± 6.5 (SD) were evaluated. The PCO rate was 42.7% in the multifocal spherical group, 28.0% in the monofocal spherical group, and 14.7% in the monofocal aspheric group. The Nd:YAG capsulotomy rate was 25.3%, 17.3%, and 4.0%, respectively. The difference in the Nd:YAG rate was statistically significantly higher in the multifocal and monofocal spherical groups than in the monofocal aspheric group ( P<.001 and P<.008, respectively) but was not significantly different between the 2 spherical IOL groups ( P = .232). The time from surgery to PCO documentation was not significantly different between the 3 groups. Intraocular lens configuration may have contributed to the difference in the PCO rate between the 2 spherical IOLs and the aspheric IOL. Based on the Nd:YAG rate as an indicator for visual significance, PCO may be less visually significant in eyes with the aspheric IOL than in eyes with 1 of the spherical IOLs.