Test-retest reliability of drug-induced sleep endoscopy

• Published in: Otolaryngology-head and neck surgery Vol. 140; no. 5; p. 646
• Main Authors: Rodriguez-Bruno, Krista, Goldberg, Andrew N, McCulloch, Charles E, Kezirian, Eric J
• Format: Journal Article
• Language: English
• Published: England 01.05.2009
• Subjects: Adult; Aged; Anesthetics, Intravenous - administration & dosage; Endoscopy - methods; Female; Humans; Male; Middle Aged; Propofol - administration & dosage; Prospective Studies; Reproducibility of Results; Sleep Apnea, Obstructive - diagnosis; Sleep Apnea, Obstructive - physiopathology; Treatment Outcome
• ISSN: 0194-5998; 1097-6817
• DOI: 10.1016/j.otohns.2009.01.012

To determine the test-retest reliability of drug-induced sleep endoscopy (DISE). Prospective cohort study. Patients with OSA underwent two separate DISE examinations. The following outcomes were measured: a global assessment of obstruction at the palate and/or hypopharynx; the degree of obstruction at the palate and hypopharynx; and the contribution of individual structures (palate, tonsils, tongue, epiglottis, and lateral pharyngeal walls) to obstruction. Thirty-two patients underwent two separate DISE examinations. The preoperative sleep study apnea-hypopnea index was 40.7 +/- 21.1, and the lowest oxygen saturation was 79.8 +/- 17.4 percent. Point estimates for the intraclass correlation coefficient analogs related to palatal obstruction ranged from 0.41 to 0.89; related to the hypopharyngeal airway, the point estimates ranged from 0.57 to 0.84. The test-retest reliability of DISE appears good, especially in the evaluation of the hypopharyngeal airway. Larger studies can generate more precise confidence interval estimates and test the generalizability of these findings.