Deep Brain Stimulation in a Patient with Parkinson's Disease and Cortical Superficial Siderosis

• Published in: Internal Medicine Vol. 61; no. 21; pp. 3277 - 3279
• Main Authors: Shiraishi, Makoto, Matsuura, Keita, Nishiguchi, Yamato, Shindo, Akihiro, Araki, Tomohiro, Kajikawa, Hiroyuki, Nakatsuka, Yoshinari, Ikezawa, Munenari, Tomimoto, Hidekazu
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.11.2022; Japan Science and Technology Agency
• Subjects: Amyloid; Cerebral amyloid angiopathy; cortical superficial siderosis; Deep brain stimulation; Hemorrhage; Internal medicine; intracerebral hemorrhage; Magnetic resonance imaging; Movement disorders; Neurodegenerative diseases; Neuroimaging; Parkinson's disease; Patients; Risk factors; Siderosis; Surgery; intracerebral hemorrhage; Parkinson's disease; cerebral amyloid angiopathy; cortical superficial siderosis; deep brain stimulation
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.9253-21

Cortical superficial siderosis (cSS) is a rare condition that is regarded as a potential magnetic resonance marker of cerebral amyloid angiopathy (CAA). We describe the case of a 68-year-old man with cSS and Parkinson's disease (PD) who subsequently exhibited incidental microhemorrhages, which were only detected on magnetic resonance imaging (MRI), at one week after deep brain stimulation (DBS) surgery. cSS is now considered to be a significant risk factor for CAA and future bleeding. Therefore, because DBS surgery is invasive and may increase the risk of intracerebral hemorrhage, the procedure should be performed carefully when managing patients with PD and CAA.