Primitive neuroectodermal tumor of the kidney in a young male: Case report and review of literature

• Published in: Urology annals Vol. 7; no. 2; pp. 236 - 239
• Main Authors: Patnaik, Nivedita, Mishra, Kiran, Saini, Pradeep, Agarwal, Nitin
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.04.2015; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Blastemal wilms; Care and treatment; Case Report; Case studies; Diagnosis; immunohistochemistry; kidney; Kidney cancer; Kidneys; Males; Neuroectodermal tumors; Patient outcomes; primitive neuroectodermal tumor; Risk factors; Tumors; Urology; India; kidney; immunohistochemistry; Blastemal wilms; primitive neuroectodermal tumor
• ISSN: 0974-7796; 0974-7834
• DOI: 10.4103/0974-7796.150537

Primitive neuroectodermal tumor of the kidney is a rare tumor. A total of approximately 79 primary renal cases have been reported to date. Primitive neuroectodermal tumors occur preferentially in the soft-tissues of the paravertebral region and chest wall, less frequently in extremities, with a slight male predominance. We report a case of primitive neuroectodermal tumor of the kidney in a 17-year-old male with a pre-operative diagnosis of renal cell carcinoma-stage 4. The patient underwent radical nephrectomy and histopathological examination revealed a highly aggressive tumor of monotonous sheets of round cells with focal areas of rosette formations and high mitotic rate with Ki67 index of 25-30%. Tumor cells were positive for CD 99 confirming the diagnosis of primitive neuroectodermal tumor. Primitive neuroectodermal tumor of the kidney needs to be kept in mind as a differential diagnosis in young adults presenting with a large kidney mass.