Polymorphic Ventricular Tachycardia with QT Interval Prolongation Due to a Brain Tumor

• Published in: Internal Medicine Vol. 60; no. 16; pp. 2633 - 2637
• Main Authors: Nakayama, Yui, Furukawa, Toshiyuki, Yamada, Marika, Takano, Makoto, Nakajima, Ikutaro, Harada, Tomoo, Akashi, Yoshihiro J
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 15.08.2021; Japan Science and Technology Agency
• Subjects: Biopsy; Brain cancer; brain tumor; Brain tumors; Cardiac arrhythmia; Case Report; Chemotherapy; Epilepsy; Hormone replacement therapy; Internal medicine; QT prolongation; Seizures; Tachycardia; Ventricle; ventricular tachycardia; ventricular tachycardia; brain tumor; QT prolongation
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.6635-20

We herein report the case of a 20-year-old man with a history of epilepsy who presented with frequent transient loss of consciousness (T-LOC) and polymorphic ventricular tachycardia (VT) with QT interval prolongation. Blood investigations revealed panhypopituitarism. Following a biopsy, he was diagnosed with brain germinoma. During the biopsy, he had an episode of polymorphous VT with QT prolongation. There was no recurrence of T-LOC following chemotherapy and hormone replacement therapy. This case indicates the importance of checking the QT interval in patients with T-LOC, including those with seizures and brain tumors, to ensure appropriate treatment.