Diagnostic methods and potential portable biosensors for coronavirus disease 2019

• Published in: Biosensors & bioelectronics Vol. 165; p. 112349
• Main Authors: Cui, Feiyun, Zhou, H. Susan
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.10.2020
• Subjects: AI assisted diagnosis; Animals; antibodies; Antibodies, Viral - analysis; antibody detection; antibody formation; antigens; Antigens, Viral - analysis; artificial intelligence; Betacoronavirus - isolation & purification; biomarkers; Biosensing Techniques - instrumentation; Biosensing Techniques - methods; biosensors; Biosensors for virus detection; chest; Chromatography, Affinity - instrumentation; Chromatography, Affinity - methods; computed tomography; Coronavirus infections; Coronavirus Infections - diagnosis; COVID-19; diagnostic techniques; disease control; electrochemistry; Environmental Monitoring - instrumentation; Environmental Monitoring - methods; Equipment Design; Humans; immunoaffinity chromatography; Lateral flow immunochromatographic strip; Pandemics; patients; Pneumonia, Viral - diagnosis; Polymerase Chain Reaction - instrumentation; Polymerase Chain Reaction - methods; quantitative polymerase chain reaction; Raman spectroscopy; Reagent Strips - analysis; reverse transcriptase polymerase chain reaction; RNA, Viral - analysis; saliva; SARS-CoV-2; screening; Severe acute respiratory syndrome coronavirus; surface plasmon resonance; throat; Tomography, X-Ray Computed - instrumentation; Tomography, X-Ray Computed - methods; transistors; vaccines; COVID-19; Lateral flow immunochromatographic strip; SARS-CoV-2; Biosensors for virus detection; AI assisted diagnosis

Timely detection and diagnosis are urgently needed to guide epidemiological measures, infection control, antiviral treatment, and vaccine research. In this review, biomarkers/indicators for diagnosis of coronavirus disease 2019 (COVID-19) or detection of severe acute respiratory syndrome coronavirus...